Lead Beneficiary: CNR (Naples, Italy)


  • to understand the mechanism that anchors chromatin loops formed by cohesin at specific sites in the human genome
  • to examine the effect of DSB-induced cohesin phosphorylation on loop extrusion
  • to elucidate the molecular mechanisms of cohesin DNA bridging by single molecule studies
  • to improve instrumentation, software and workflow for single-molecule biophysical studies